Markstrom will miss his second straight game with an upper-body injury, which likely means that David Rittich will face the Maple Leafs on Wednesday. Rittich posted a 34-save shutout on Monday, so expect him to get all of the starts until Markstrom can re-join the team.
Hischier is available to make his season debut on Saturday but head coach Lindy Ruff would not confirm whether or not he will play. If he does play, expect Hischier to replace either Nathan Bastian or Nick Merkley and he could be eased into a bottom-6 role, since it's his first game since March 10th of last year.
Noesen will play for the first time since January 28th, replacing Marcus Sorensen on the fourth line. Noesen has failed to record a point in four games this season.