Brassard returned to the lineup on Thursday, playing 16:40 TOI with three shots in the loss to the Penguins. However, he had a flare-up of his hip issue and is considered doubtful to be in the lineup on Saturday.
Giroux will miss Tuesday's game in Anaheim after being entering COVID-19 protocol. With Giroux out, Kevin Hayes will likely centre the top line and Morgan Frost, Scott Laughton and Patrick Brown will serve as the Flyers' centre.
The Senators COVID-19 protocol list now sits at eight players, with Chabot, Chris Tierney and Zach Sanford entering protocol on Monday.
The Senators are set to play Saturday in Toronto but it looks like they'll have to do it without their No.1 centre. Tim Stuetzle and Nick Paul will likely play larger roles while Norris is sidelined.
Perron has not played since November 26th due to an upper-body injury but will be back on the top line with Ryan O'Reilly and Brandon Saad on Wednesday. Perron has scored seven goals with 11 assists (18 points) in 20 games before getting hurt.
Boucher was the No.10 overall pick in this year's NHL Entry Draft and has scored two goals with one assist in 17 games with Boston University. According to Jeff Marek of Sportsnet, Boucher will be heading to the Ottawa 67's (OHL).
Brassard, Carter Hart and Scott Laughton join Sean Couturier, who was added to the protocol list on Sunday. Despite losing four regulars to start the week, they are expected to get Kevin Hayes and Morgan Frost back in time for Wednesday's game.
Forsberg joins Filip Gustavsson in protocol, which left the Senators with no goalies in Monday's practice. They recalled Matt Murray from the AHL on Tuesday and he would be in-line to start Friday if Forsberg and Gustavsson are unavailable.
Cousins is the latest Predators player to be added to the COVID-19 protocol list and will not be available on Thursday. The Predators will likely have to play a player short unless they recall another forward from Milwaukee (AHL).