Nugent-Hopkins has missed the last six games with a lower-body injury but is set to play Tuesday in Vancouver. The Oilers will go with a different look, centring the third line with Zack Kassian and Brendan Perlini, instead of playing with Leon Draisaitl.
Brown is expected to be sidelined until early-to-mid February after breaking his jaw in warmups last Thursday. Tyler Ennis has been bumped up into the top-6 to replace Brown.
The Oilers woes continue with Skinner getting added to the COVID-19 protocol list on Monday morning. With Mike Smith also banged up right now, expect Mikko Koskinen to start on Thursday.
Brown was hit in the face with a puck in warmups on Wednesday and played the game with a broken jaw, scoring one goal with one assist in 19:28 TOI. He'll miss some time according to head coach DJ Smith but could be replaced by Tim Stützle (COVID-19 protocol) on Saturday.
Walman has been a healthy scratch recently and probably wasn't going to play anyways but he won't be available for the next two games.
Murray has not played since November 27th, when he suffered a lower-body injury his first shift vs. the Predators. Murray, who has four assists in 17 games this season, will replace Jack Johnson on the blueline.
Nugent-Hopkins is expected to be sidelined through the month of January, which is a terrible blow for an Oilers team that is also without Connor McDavid (COVID-19 protocol) right now.
Ryan joins Connor McDavid and Tyson Barrie in COVID-19 protocol and will not play Wednesday. With two centres out, Kyle Turris and Colton Sceviour will likely have to shift to the middle of the ice.
The Oilers are in the middle of a tough stretch and things will get more difficult on Wednesday with McDavid, Tyson Barrie and Derek Ryan all in COVID-19 protocol. Ryan McLeod is expected to move into the top-6 with McDavid out.
