Joseph suffered an undisclosed injury in Detroit on Tuesday and head coach DJ Smith said his injury is a "little worse than we thought" and that they may not get him back this season.
Krug has missed the last 10 games with an upper-body injury but there's a "good chance" he plays Tuesday. It would be a big game for Krug, who would be returning to Boston for the first time since signing with St. Louis prior to the 2021 season.
MacEachern suffered an upper-body injury vs. the Wild on Friday, missed Saturday's game and will not travel on the Blues' two-game road trip. Jordan Kyrou replaced him on Saturday and will obviously remain in the lineup on Tuesday.
Schueneman was a healthy scratch in Toronto on Saturday but is expected to replace Chris Wideman in the lineup on Monday. Schueneman has tallied six points (2G / 4A) in 21 games this season.
Kyrou missed the morning skate with an illness but head coach Craig Berube did not rule him out for Friday's game. Monitor his status as the Blues hit the ice for warmups (8:00 PM ET) and expect Alexei Toropchenko to move up to the third line if Kyrou can't play.
Kyrou has missed the last three games with an illness but will play Monday vs. the Coyotes. Kyrou was back on the third line and second power-play unit in Monday's practice and has 19 points (4G / 15A) in his last 17 games.
Kyrou missed Wednesday's game in Vancouver but will be a game-time decision on Friday. The Blues held an optional morning skate this morning, so there wasn't any indication on whether or not Kyrou will be available in Edmonton.