Matthews suffered a lower-body injury after being hit by Nikita Zadorov halfway through the second period of Tuesday's game and was unable to return. The 28-year-old Matthew has 14 points (9G / 5A) in 17 games this season and is expected to be sidelined for at least one week. Max Domi has been elevated to Toronto's top powerplay unit to replace the injured Matthews.

Jenner was limited to only 7:21 time-on-ice in the Blue Jackets' most recent game, exiting in the second period due to an upper-body injury. The 32-year-old has battled injuries over the past few years. He has 10 points (3G / 7A) in 16 games this season.

Burakovsky was absent from practice on Wednesday, tending to an undisclosed injury, and his status was uncertain for the Blackhawks' game against the New Jersey Devils. Burakovsky has been outstanding lately, playing on a line with Connor Bedard, scoring 10 points (5G / 5A) in his last seven games.

The Lightning are dealing with a handful of injuries on Wednesday, with Victor Hedman and Anthony Cirelli also being unavailable. Holmberg has appeared in 15 games this season, logging one goal and four assists.

Cirelli suffered an upper-body injury in last Thursday's win over Vegas and has not played since. The 28-year-old Cirelli has 11 points (7G / 4A) in 14 games this season.

Hedman played a season-low 17:51 time-on-ice in Tampa Bay's most recent game, and has been absent from the team's last two practices, tending to an undisclosed injury. The 34-year-old Hedman has 12 points (0G / 12A) through 15 games this season.

Foerster was drafted 23rd overall by the Flyers in the 2020 NHL Entry Draft and has shown strides towards becoming a reliable offensive producer at the NHL level. After scoring a career-high 43 points (25G / 18A) in 81 games last season, he was off to a strong start in 2025-26, with seven points (4G / 3A) in 11 games. He returned to practice on Tuesday and will likely return to his regular deployment in the Flyers' top-six on Wednesday against the Edmonton Oilers.

Daccord has not played since November 5th due to an upper-body injury, but appears to be inching closer to a return after practicing on Wednesday. Matt Murray has seen most of the action between the pipes since Daccord's injury and will likely continue to do so until Daccord returns.

Nichushkin exited Tuesday's 4-1 win over the Anaheim Ducks due to a lower-body injury after only 12:57 time-on-ice. The 30-year-old Nichushkin has 12 points (5G / 7A) in 17 games this season, and has been more productive lately, with nine points (3G / 6A) in his last 10 games. Colorado's head coach, Jared Bednar, was unable to provide a concrete update on Nichushkin's timeline, other than stating he will "miss some time."

Erne was injured in the third period of the Stars' 3-2 win over the Ottawa Senators on Tuesday, exiting the game with 8:36 time-on-ice. The 30-year-old Erne has been an effective fourth-line player for the Stars, scoring three points (2G / 1A) in 14 games this season.

Burakovsky was absent from practice on Wednesday, tending to an undisclosed injury, and his status is uncertain for the Blackhawks' game against the New Jersey Devils. Burakovsky has been outstanding lately, playing on a line with Connor Bedard, scoring 10 points (5G / 5A) in his last seven games.

Hyman missed the second half of last year's playoffs after enduring an upper-body injury and has yet to play in the 2025-26 season. At the beginning of training camp, Head Coach Kris Knoblach stated he is hopeful the 32-year-old can return in early November, a timeline that seems to be holding true, as Head Coach Knoblach stated he may return to the lineup as early as Thursday. Hyman is just one season removed from a 54-goal campaign in 2023-24 and will hope to get off to a hot start when he is able to return.

Fleury has been a regular for the Jets this season, but exiting Tuesday's 5-3 win over the Vancouver Canucks after only 6:38 time-on-ice due to an upper-body injury. The 29-year-old Fleuery has played 15 games this season. He has not played more than 47 games since his rookie season in 2017-18.

Chabot suffered an upper-body injury in the first period of Tuesday's game and was unable to return. He will not play on Thursday against the Boston Bruins, and is being reevaluated. The 28-year-old defenseman has 10 points (2G / 8A) in 17 games this season.

Foerster was drafted 23rd overall by the Flyers in the 2020 NHL Entry Draft and has shown strides towards becoming a reliable offensive producer at the NHL level. After scoring a career-high 43 points (25G / 18A) in 81 games last season, he was off to a strong start in 2025-26, with seven points (4G / 3A) in 11 games. He returned to practice on Tuesday and could return to his regular deployment in the Flyers' top-six on Wednesday against the Edmonton Oilers.

Hamilton left last Thursday's game vs. Montreal with an undisclosed injury, and has been sidelined since. He is expected to miss at least the next three games while the team is on a road trip. With Hamilton out, Simon Nemec has seen an expanded role, including deployment on the team's top powerplay unit.

Brown played the first 11 games for the Devils this season, but has not played since. The 31-year-old Brown is averaging 15:47 time-on-ice and has six points (5G / 1A) in 11 games this season. He will likely miss the next three games while the team is on the road.

Andersen seemed like he did not want to exit the game after a collision, indicating that he may have been pulled for precautionary reasons by a concussion spotter. That said, head coach Rod Brind'Amour has yet to provide an update on Andersen's status. With the Hurricanes already carrying three goalies between Andersen, Pyotr Kochetkov, and Brandon Bussi, the team likely won't rush Andersen back into the lineup if he is not 100%.

Demko has battled a myriad of injuries over the previous several seasons and will be sidelined once again. The positive news is this injury is not related to the injury that kept him out of games this past weekend, nor the injury that sidelined him for half of the 2024-25 season. Expect Kevin Lankinen to see a heavy workload between the pipes during Demko's absence.

Nichushkin exited Tuesday's 4-1 win over the Anaheim Ducks due to a lower-body injury after only 12:57 time-on-ice. The 30-year-old Nichushkin has 12 points (5G / 7A) in 17 games this season, and has been more productive lately, with nine points (3G / 6A) in his last 10 games. Colorado's head coach Jared Bednar was not able to provide a concrete update on Nichushkin's timeline.